Titlebook: Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites; Juan-Francisco Martín,Carlos García-Estrada,Susann Book 2014 Springer

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Lovastatin, Compactin, and Related Anticholesterolemic Agents,-methyl-glutaryl-CoA reductase, a key enzyme involved in the regulation of cholesterol biosynthesis, and have spawned a revolution in cholesterol-lowering medications. The biosynthetic pathways of lovastatin and compactin have been studied in great detail, and there are a number of remarkable featur

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Meroterpenoids,c pathways is important for future drug discovery. Recent advances in genome sequencing have revealed many biosynthetic gene clusters for fungal meroterpenoids, thus providing clearer insights into the enzymes that construct these structurally complex molecules and the genetic bases for the producti

hemoglobin

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Fungal NRPS-Dependent Siderophores: From Function to Prediction,hat provide a high-affinity iron uptake system and safe intracellular storage and transport mechanisms to gain a competitive advantage. Here, we discuss the function of siderophores in relation to fungal iron uptake mechanisms and their importance for coexistence with host organisms. The chemical na

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Zhen-Zhen Li,Zhuo-Yao Zhong,Lian-Wen Jinunderlying the process of strain improvement. These studies have revealed that the increased productivity of industrial strains of . lays on a careful rebalancing of metabolic pathways, which proves the versatility of this filamentous fungus for the production of the twentieth century magic bullet,

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Ilias S. Kotsireas,Panos M. Pardalosrters, and other regulators that are involved in both cephalosporin C biosynthesis and fungal morphology. Despite strong progress, our understanding of the regulatory mechanisms controlling cephalosporin C biosynthesis remains incomplete. Future work must therefore focus on the application of advanc

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