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Titlebook: Bioreactor Systems for Tissue Engineering; Cornelia Kasper,Martijn Griensven,Ralf Pörtner Book 2009 Springer-Verlag Berlin Heidelberg 2009

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Entscheidungs- und Organisationstheorieor transplantation. These strategies aim to grow a complex tissue with the appropri ate mechanical integrity necessary for functional load bearing. Monolayer culture systems lack correlation with the in vivo environment and the naturally occur ring cell phenotypes. Part of the development of more re
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,Führungsperformance in Zeiten des Umbruchs,rts have to be undertaken to improve healing. For this purpose, tissue engineering may be an option. In order to stimulate cells to form a bone tissue several factors are needed: cells, scaffold, and growth factors. Stem cells derived from bone marrow or adipose tissues are the most useful in this r
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,Führungsperformance in Zeiten des Umbruchs, (ACT) involved the transplantation of in vitro expanded chondrocytes to cartilage defects. The second generation involves the seeding of chondrocytes in a three-dimensional scaffold. The technique has several potential advantages such as the ability of arthroscopic implantation, in vitro pre-differ
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https://doi.org/10.1007/978-3-8349-9913-9three-dimensional tissues in vitro. Here formation of cartilage-carrier-constructs is used to demonstrate that the quality of the tissue can be significantly improved by using optimized culture conditions (oxygen concentration, growth factor combination) as well as special bioreactor techniques to i
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https://doi.org/10.1007/978-3-8349-3706-3The following chapter summarizes principles of fluid dynamics in bioreactor design with a focus on mammalian cell-culture systems.
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Prognoses: Changing Relationships,undamental knowledge gained through the use of well-defined and controlled bio-reactor systems at the research level will be essential to define, optimize, and moreover, . the key processes required for efficient manufacturing models.
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