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Titlebook: Biophysics of the Pancreatic β-Cell; Illani Atwater,Eduardo Rojas,Bernat Soria Book 1986 The Editor(s) (if applicable) and The Author(s),

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期刊全称Biophysics of the Pancreatic β-Cell
影响因子2023Illani Atwater,Eduardo Rojas,Bernat Soria
视频video
学科分类Advances in Experimental Medicine and Biology
图书封面Titlebook: Biophysics of the Pancreatic β-Cell;  Illani Atwater,Eduardo Rojas,Bernat Soria Book 1986 The Editor(s) (if applicable) and The Author(s),
影响因子Pancreatic a-cell biophysics has undergone a veritable informa­ tion explosion in the past two years. Single channel and macroscopic currents have become easily accessible following the introduction of the patch clamp technique. In addition to this new approach, further development of techniques for optical measurements, ion-sensitive microelectrodes, permeabilized cells and mathematical modelling have recently added to the now classical techniques of membrane potential recording and tracer flux measurement. The International Workshop on Biophysics of the Pancreatic a-Cell held in Alicante (Spain) on Sep­ tember 30 - October 1, 1985, has now given us the opportunity to share experiences with these new techniques applied to the a-cell. Further­ more this was the first occasion for most of the groups doing patch­ clamp studies of the a-cell to decide on appropriate nomenclature and to debate the different characteristics of the a-cell ionic channels. To make this information available to the larger scientific community a record of the meeting has been assembled in this book. It is a collection of research papers by leading scientists at the meet­ ing working on biophysical, biochemic
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Guatemala, an Alternation in Continuitysmitters. Examples include secretory granules from chromaffin cells,. pancreatic B-cells,. platelets. and mast cells. We have recently shown. that it is possible to obtain real-time measurements of the kinetics of secretion of vesicle contents by monitoring ATP release from stimulated medullary chro
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https://doi.org/10.1007/978-94-007-0504-3e recent review by Henquin & Meissner.). Microelectrode recordings have shown that in the absence of glucose the β-cell is electrically silent. Increasing plasma glucose depolarises the membrane by an amount that is dependent on the glucose concentration and electrical activity is initiated when thi
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,Adult ESL Immigrant Learners …, the cell, mobilizes calcium from stores within the cell and thus triggers the exocytosis of insulin.. Calcium uptake occurs when glucose depolarizes the β-cell membrane to trigger periodic bursts of calcium action potentials.. The mechanisms which couple glucose metabolism to the depolarization hav
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https://doi.org/10.1007/978-3-031-46105-7 is to evoke membrane depolarization. followed by a cyclical pattern of electrical activity consisting of slow waves of depolarization with action potential-like spikes.. Tracer flux studies have indicated that glucose metabolism is associated with a decrease in membrane K. permeability. and Ashcrof
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https://doi.org/10.1007/978-3-031-56118-4al models of diabetes mellitus.. They all have hyperglycemia, hyperinsulinemia, and obesity as common metabolic characteristics.. Among these mouse mutants, particular attention has been paid to the homozygous diabetes mouse carrying the diabetes gene (commonly known as the db/db mouse), and the hom
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