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Titlebook: Biophysics of Infection; Mark C. Leake Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Natu

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发表于 2025-3-21 18:37:14 | 显示全部楼层 |阅读模式
期刊全称Biophysics of Infection
影响因子2023Mark C. Leake
视频video
发行地址Provides detailed reviews and protocols written by leading international experts.Explores basic molecular biological aspects as well as physical methods and mathematical analysis.Offers up-to-date inf
学科分类Advances in Experimental Medicine and Biology
图书封面Titlebook: Biophysics of Infection;  Mark C. Leake Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Natu
影响因子This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and prot
Pindex Book 2016
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发表于 2025-3-22 00:05:02 | 显示全部楼层
Single-Molecule Observation of DNA Replication Repair Pathways in ,,ronidazole causes single- and double-stranded breaks in DNA. To understand how bacteria respond to these drugs, it is important to understand the repair processes utilised when DNA replication is blocked. We have used tandem . operators inserted into the chromosome bound by fluorescently labelled .
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,What Is the ‘Minimum Inhibitory Concentration’ (MIC) of Pexiganan Acting on ,?—A Cautionary Case Stmeasurements. These results led to a detailed study of the effect of pexiganan on the growth curve of ., using a plate reader and manual plating (i.e. time-kill curves). The measured growth curves, together with single-cell observations and peptide depletion assays, suggested that addition of a sub-
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Using Biophysics to Monitor the Essential Protonmotive Force in Bacteria,ference across biological membrane. In bacteria, protonmotive force couples to metabolism and ATP production. Moreover, protonmotive force directly provides driving energy of bacterial flagellar motor that is critical for bacterial motility and infection. Due to the small size of bacterial cells, th
发表于 2025-3-22 20:55:13 | 显示全部楼层
The Type I Restriction Enzymes as Barriers to Horizontal Gene Transfer: Determination of the DNA Tanging to different clonal complexes. The livestock-associated clonal complexes CC133/771 and CC398 contain Type I RM systems not found in human MRSA strains as yet but at some point transfer will occur. When this does take place, horizontal gene transfer of resistance will happen more easily between
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Biomechanical Analysis of Infectious Biofilms,hanical properties of their polymeric matrix. Linking the various physical and chemical microscopic interactions to macroscopic deformation and failure modes promises to unveil design principles for novel therapeutic strategies targeting biofilm eradication, and provide a predictive capability to ac
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发表于 2025-3-23 09:34:00 | 显示全部楼层
,Bacterial Surfaces: Front Lines in Host–Pathogen Interaction,hin and attached to the cell membrane are essential for ensuring that the overall homeostasis of the cell is maintained. However, many surface components of the bacterial cell also have an indispensable role mediating interactions of the bacteria with their immediate environment and as such are esse
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