Titlebook: Biomarkers of the Tumor Microenvironment; Lars A. Akslen,Randolph S. Watnick Textbook 2022Latest edition The Editor(s) (if applicable) and

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Lymphatics in Malignant Tumorsion of an immune tolerance, which may explain why high lymphatic vessel density is often associated with poor prognosis. Therefore, it is likely that lymphatic vessels play multiple complex roles at different stages of cancer development, and that the research on the impact of lymphatics on cancer w

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Role of Lymphocytes in Cancer Immunity and Immune Evasion Mechanismsuch as macrophages, and granulocytes to eliminate cancer. However, CD8+ T cells with the help of CD4+ T cells represent the major effector mechanism of anti-tumor immunity. On the other hand, regulatory T cells, a subset of CD4+ T cells, are involved in promoting tumor growth by suppressing both CD4

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