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Titlebook: Biomarkers in Neoplastic Neuropathology; Fausto Rodriguez,Cheng-Ying Ho Book 2016 Springer International Publishing Switzerland 2016 Brain

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期刊全称Biomarkers in Neoplastic Neuropathology
影响因子2023Fausto Rodriguez,Cheng-Ying Ho
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发行地址Describes the techniques available for clinical and experimental evaluation of biomarkers in brain neoplasms.Discusses the diagnostic, prognostic, and predictive biomarkers applicable to specific tumo
图书封面Titlebook: Biomarkers in Neoplastic Neuropathology;  Fausto Rodriguez,Cheng-Ying Ho Book 2016 Springer International Publishing Switzerland 2016 Brain
影响因子This book is a rich source of information on biomarkers applicable to the pathology of neoplastic disorders of the brain. Thorough descriptions are provided of the techniques currently available for clinical and experimental evaluation of biomarkers in brain neoplasms, including in situ hybridization, array-based methods, methylation profiling, next-generation sequencing, and practical gene panels. Incorporation of multiple biomarkers in the development of molecular subgroups with biologic and therapeutic relevance is also discussed. A section on biobanking covers the equally important topic of optimal preservation of tissue and includes consideration of ethical considerations raised by the use of tissue obtained in clinical settings. The closing section discusses the major categories of neoplastic disorders involving the nervous system, with emphasis on diagnostic, prognostic, and predictive biomarkers used in the pathologic evaluation of different types of brain tumor.
Pindex Book 2016
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Biomarkers Applied to Specific Tumor Types,ncer Genome Atlas have started to clarify the basic drivers in the major tumors involving the nervous system. Major biomarkers that have been widely accepted in the area of diffuse gliomas include . promoter methylation, . mutations, and 1p19q co-deletion that have become standard of care for molecu
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Fausto Rodriguez,Cheng-Ying HoDescribes the techniques available for clinical and experimental evaluation of biomarkers in brain neoplasms.Discusses the diagnostic, prognostic, and predictive biomarkers applicable to specific tumo
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https://doi.org/10.1007/978-3-662-02087-6earch settings. Immunohistochemistry and in situ hybridization have been particularly applied in routing diagnostic settings, given their early optimization to formalin-fixed paraffin-embedded tissues, and the preservation of tumor and tissue morphology. Other robust techniques including array-based
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https://doi.org/10.1007/978-3-662-02087-6nning, resources, and active involvement of neuropathology. Samples stored for neoplastic neuropathology in particular include snap-frozen and formalin-fixed paraffin-embedded (FFPE) tissues, as well as cerebrospinal fluid (CSF), blood, and saliva for biomarker discovery and nonneoplastic DNA contro
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