Titlebook: Biology of Stem Cells and the Molecular Basis of the Stem State; Dov Zipori Book 2009 Humana Press 2009 biology.cancer.cell.cell biology.c

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Stem Cells with No Tissue Specificity,ssue non-specific manner. These cells may be multipotent [such as the mesenchymal stromal cells (MSCs) that give rise to a variety of mesodermal progeny (for example bone, cartilage, and muscle)]. An additional type, of non-tissue-specific stem cells, consists of pluripotent cells, i.e. cells capabl

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A Critical Analysis of Properties Commonly Ascribed to Stem Cells,tipotency is often found in committed progenitor cells. By contrast, stem cells are unique in their pluripotency and relatively high plasticity. Pluripotent stem cells stand out, and profoundly differ from all other cells that exist in the organism. On the basis of these observations, an alternative

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,The Stem State: Stemness as a State in the Cell’s Life Cycle,ing selfrenewal divisions of cells existing in the stem state. The stem cell niche enforces the process of self-renewal. An alternative path leading to the stem state is dedifferentiation of cells, at later stages of the differentiation cascade. Thus, cellular plasticity entailing dedifferentiation

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2196-8985 in the broad field of biology and is not meant for stem cel.Biology of Stem Cells and the Molecular Basis of the Stem State concentrates upon adult stem cells, particularly on mesenchymal cell populations, which is the author’s area of expertise. The text offers the reader a detailed description of

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https://doi.org/10.1007/b138546a niche, in certain stem cell types, raises the question as to whether niche dependence is a stem cell property. Alternatively, as shown in the following chapters, some of the cells defined thus far as stem cells and are not niche dependent, should not be regarded as members of the stem cell category.

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,Psychopharmaka und Fahrtüchtigkeit,potent stem cells stand out, and profoundly differ from all other cells that exist in the organism. On the basis of these observations, an alternative definition of stemness is presented in the next chapter.

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