Titlebook: Biology of Stem Cells and the Molecular Basis of the Stem State; Dov Zipori Book 2009 Humana Press 2009 biology.cancer.cell.cell biology.c

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https://doi.org/10.1007/978-3-642-13044-1eral of the most studied organ-specific stem cells, such as neuronal stem cells (NSCs), skin stem cells, and intestinal stem cells, are described. Like HSCs, that give rise to all blood cell types, intestinal stem cells differentiate to the variety of mature cells found in the intestine, and are the

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,Psychopharmaka und Fahrtüchtigkeit,ssue non-specific manner. These cells may be multipotent [such as the mesenchymal stromal cells (MSCs) that give rise to a variety of mesodermal progeny (for example bone, cartilage, and muscle)]. An additional type, of non-tissue-specific stem cells, consists of pluripotent cells, i.e. cells capabl

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https://doi.org/10.1007/b138546gonads. The various types of mammalian stem cell niches, and their cellular and molecular structure are discussed. The lack of complete dependence on a niche, in certain stem cell types, raises the question as to whether niche dependence is a stem cell property. Alternatively, as shown in the follow

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,Psychopharmaka und Fahrtüchtigkeit,ing selfrenewal divisions of cells existing in the stem state. The stem cell niche enforces the process of self-renewal. An alternative path leading to the stem state is dedifferentiation of cells, at later stages of the differentiation cascade. Thus, cellular plasticity entailing dedifferentiation

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https://doi.org/10.1007/b138546tter are continuously proliferating, while normal stem cells never do. TICs are either poorly differentiating or lack differentiation capacity altogether. Their biology is therefore a mirror image of stemness.

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Multipotency and Tissue-Specific Stem Cells,eral of the most studied organ-specific stem cells, such as neuronal stem cells (NSCs), skin stem cells, and intestinal stem cells, are described. Like HSCs, that give rise to all blood cell types, intestinal stem cells differentiate to the variety of mature cells found in the intestine, and are the