Titlebook: Biology of Aging; Robert Zwilling,Cesare Balduini Book 1992 Springer-Verlag Berlin Heidelberg 1992 Alzheimer.alzheimer‘s disease.biology.b

走调

Aging and Electron Leakage Outside Mitochondrial Energy-Transducing Sequence,ctorial translocation of protons across the inner membrane. This proton electrochemical potential (Δ.H .) drives ATP synthesis, ion translocation, and protein importation. At three steps along the electron transfer chain, represented by protein-lipid enzyme complexes I, III, and IV, oxidative energy

Inordinate

粘连

,Unravelling the Molecular Defect in Alzheimer’s Disease,creased interest in the biology of aging and in the pathology of age-associated diseases. Among these, Alzheimer’s disease (AD) is the most frequent cause of dementia and as such already the fourth leading cause of death. Its pathological basis was defined by Alois Alzheimer in 1907 in a case report

Glossy

,Expression of Alzheimer’s Amyloid Gene in Development, Aging, and Alzheimer’s Disease,is correlated with massive deposition of fibrillar aggregates of the amyloid .A4 protein. These amyloid deposits occur in the brain as intracellular neurofibrillary tangles, extracellular amyloid plaque cores, and cerebrovascular amyloid [7, 12, 20, 21, 23, 42–44, 46, 47]. The .A4 peptide consists o

adequate-intake

Aging Brain and Hypothalamic-Pituitary-Adrenal Function: Implications for Dementia of the Alzheimerally work at a sufficient level but fail to respond adequately to any further environmental demand [1]. Age primarily affects brain function: impaired cognition represents a common feature of late life, readily encountered in clinical practice.

Frequency

积习难改

Arteriosclerosis and Aging. Distribution Pattern of Atherosclerosis in Various Arteries,ge-related alterations of tissues, then arteriosclerosis seems to be an aging phenomenon [4, 11]. Since we are the only species which suffers from arteriosclerosis, it appears that this disease is a consequence of a generalized evolutionary development related to aging.

MAPLE

Physiological and Surgical Aspects of the Geriatric Patient,ed on the one hand a progressive decrease in birth indices and on the other an increase in life expectancy. The average length of life in Italy has increased to 78 years for women and to 71 years for men. In the world, 10% of the population is over 65 years old.

Brocas-Area

Noctambulant

Hormone Production in Neuroendocrine Tumours of Transgenic Mice,d of variably differentiated cells that share a number of morphologic markers normally expressed by neurons and endocrine cells [3, 4]. In laboratory animals, the occurrence of neuroendocrine tumours, which is virtually null in young animals, shows an extraordinary increase with age [5, 6]. The reas