期刊全称 | Biological Small Angle Scattering: Techniques, Strategies and Tips | 影响因子2023 | Barnali Chaudhuri,Inés G. Muñoz,Volker S. Urban | 视频video | | 发行地址 | Includes the principles and theoretical background of various SAS techniques.States practical aspects that range from sample preparation to data publication.Covers techniques for improving data qualit | 学科分类 | Advances in Experimental Medicine and Biology | 图书封面 |  | 影响因子 | This book provides a clear, comprehensible and up-to-date description of how Small Angle Scattering (SAS) can help structural biology researchers. SAS is an efficient technique that offers structural information on how biological macromolecules behave in solution. SAS provides distinct and complementary data for integrative structural biology approaches in combination with other widely used probes, such as X-ray crystallography, Nuclear magnetic resonance, Mass spectrometry and Cryo-electron Microscopy. The development of brilliant synchrotron small-angle X-ray scattering (SAXS) beam lines has increased the number of researchers interested in solution scattering. SAS is especially useful for studying conformational changes in proteins, highly flexible proteins, and intrinsically disordered proteins. Small-angle neutron scattering (SANS) with neutron contrast variation is ideally suited for studying multi-component assemblies as well as membrane proteins that are stabilized in surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatograph | Pindex | Book 2017 |
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