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Titlebook: Biological Effects and Physics of Solar and Galactic Cosmic Radiation; Part A Charles E. Swenberg,Gerda Horneck,E. G. Stassinopo Book 1993

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978-1-4613-6266-1Springer Science+Business Media New York 1993
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Progress in the Extrapolation of Radiation Cataractogenesis Data Across Longer-Lived Mammalian Speciary risks of extended missions beyond the protection of the terrestrial magnetosphere. Exposures to high fluxes of solar protons during the projected mission to Mars, for example, could result in vision-impairing lenticular opacities late in the life span after the career missions of the astronauts are over (Lett ., 1991).
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Does the Topology of Closed Supercoiled DNA Affect its Radiation Sensitivity? agarose gel electrophoresis. Form-I DNA for all topoisomers decreased exponentially with increasing dose. The radiation sensitivity (1/D.) was dependent on the average linking difference (ΔL) associated with a given supercoiled family. For ∣ΔL∣ < 2.5 the radiation sensitivity of DNA decreased with
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Thymine Dimer Formation Mediated by the Photosensitizing Properties of Pharmaceutical Constituentsical constituents, such as the sunscreen absorbers para-aminobenzoic acid, Uvinul DS49, Eusolex 232 and the tranquillizer chlorpromazine, have the potential to photosensitise thymine dimerisation in thymine-containing systems. The yields of thymine dimer, obtained from the UV-irradiation of thymine
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The Assay of 2’ Deoxyuridine-3’-Monophosphate (dUMP) by 3’ Phosphorylation and Two Dimensional Thin amination of deoxycytidine, remains in DNA via deficient uracil glycosylase excision repair, or diminished scavenging by thymidylate synthetase, dUTPase and/or dihydropyrimidine dehydrogenase activities. The assessment of dUMP adduct formation and normal base composition is carried out by “shot-gun”
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