Titlebook: Biological Dosimetry; Cytometric Approache Wolfgang G. Eisert,Mortimer L. Mendelsohn Conference proceedings 1984 Springer-Verlag Berlin Hei

Conflict

,Kinetik und Dynamik der Mehrkörpersysteme,ement for a method to estimate directly the mutation rate in some readily available human tissue such as peripheral lymphocytes and such a technique would be of inestimable value in the screening of individuals exposed, through accident or occupation, to genotoxic agents.

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https://doi.org/10.1007/978-3-642-92720-1. They demonstrate that automation of the micronucleus assay is feasable. Moreover, DNA content distributions of micronuclei exposed to graded doses of ionizing radiation show variations that may be interpreted in terms of different mechanisms for radiation induced chromosome damage.

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Flow Cytometric Detection of Aberrant Chromosomescontrol and irradiated Chinese hamster cells and stained with propidium iodide. Heterogeneously occurring dicentric chromosomes were detected by their shapes (two centromeres). The frequencies of such chromosomes estimated by slit-scan flow cytometry correlated well with the frequencies determined by visual microscopy.

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