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Titlebook: Biologic and Systemic Agents in Dermatology; Paul S. Yamauchi Book 2018 Springer International Publishing AG 2018 systemic dermatology.bio

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https://doi.org/10.1007/978-3-322-93540-3l are useful to determine short-term efficacy and side effects but with the relatively low numbers of patients may not provide realistic data on rare adverse events. In addition, a significant percentage of patients not eligible for clinical trials are placed on biologic therapy post-approval. Conti
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Kinderarmut in Ost- und Westdeutschlanderapies in dermatology. Understanding the basic principles of pharmacoeconomics and how they apply to dermatology is important for all dermatologists and medical trainees. In this chapter, we review the key concepts of pharmacoeconomics and give examples of these as they pertain to systemic therapy
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Von der Nachkriegsnot zur Familienpolitik, thus the manufacturing of biologics is a complex process. This chapter discusses the multistep approach used to manufacture biotechnology-derived biologics. The chapter also discusses biosimilars and the complexity of their development and manufacturing along with highlighting the differences betwe
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Kinderarmut in der Wohlfahrtsgesellschaft2]. CD4+ T helper cells, called T helper (Th) 17 cells, are important in the pathogenesis of psoriasis [2–5]. Interleukin (IL)-23 stimulates survival and proliferation of Th17 cells and thus serves as a key upstream cytokine regulator for this disease. Within psoriatic skin lesions, IL-23 is overpro
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Hedi Colberg-Schrader,Ingrid Kurznot been fully elucidated, research has unequivocally shown that psoriasis represents a bona fide T cell-mediated disease. The recent discovery of a set of pathogenic T cells that produce high levels of interleukin-17 in response to interleukin-23 led to a major paradigm shift in the pathogenic mode
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Einleitung: Kinderarmut und Bildungd indeed pocketbook [1–4]. Moderate-to-severe psoriasis has also been associated with multiple comorbidities including the metabolic syndrome, cardiovascular disease, depression, and psoriatic arthritis [5–9] (Fig. 16.1). For patients with moderate-to-severe psoriasis (>10% body surface area involve
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