Titlebook: Bioinformatics of Genome Regulation and Structure; Nikolay Kolchanov,Ralf Hofestaedt Book 2004 Springer Science+Business Media New York 20

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Compositional Asymmetries and Predicted Origins of Replication of the , Genomeat the observed tendency is mostly a result of a clustering of the determined base skew polarity switches. It is concluded that the GC-skew does not give additional information about the location of chromosomal origins of replication in ..

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Transcription Regulatory Regions Database (TRRD): Description of Transcription Regulation and the Ma. They are stored in seven SRS tables: TRRDGENES, TRRDUNITS, TRRDEXP, TRRDSITES, TRRDFACTORS, TRRDLCR, and TRRDBIB. The main tool for search of and navigation through TRRD is the Sequence Retrieval System (SRS). A hierarchical structure of dictionaries and thesauri has been developed to provide additional options for data retrieval.

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Logical Analysis of Data as a Predictor of Protein Secondary Structuresoal of the analysis described in this paper is to create a system that allows for receiving as the output the protein secondary structure, based on its primary structure being an input, and for finding rules responsible for this effect.

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Macromolecular Modeling as a Tool for Expanding Bioinformatics Databasesolvent (IS) models has been developed for calculating free energies of protein and nucleic acid conformations. A protocol for calculating context-dependent DNA conformational parameters has been developed.

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Nucleosomal DNA Organization: An Integrated Information Systemositioning Region Database, compiling the available experimental data on locations and characteristics of nucleosome formation sites as well as detailed information on other factors that influence nucleosome positioning, and (2) NucleoMeter software package for recognition of these sites. The system

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Using Change in Local DNA Sequence Complexity as a Pointer to the Mechanism of Mutagenesis in Inheri of the remainder involves the insertion of novel bases that serve to alter the reading frame leading to premature termination of translation. A relatively uncommon type of mutation is the ., a complex lesion that appears to represent a combination of micro-deletion and micro-insertion. In the prese

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Properties of Insertion Regions of , LTR Retrotransposons2 families, namely, . (.), . (.), ., and ., and to detect the properties that might determine why these regions are preferable for integration of a particular LTR retrotransposon. Samples of genomic sequences with a length of 60 bp containing 4–5-bp target sites ., which are duplicated during integr

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