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Titlebook: Bioinformatics of Genome Regulation and Structure; Nikolay Kolchanov,Ralf Hofestaedt Book 2004 Springer Science+Business Media New York 20

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期刊全称Bioinformatics of Genome Regulation and Structure
影响因子2023Nikolay Kolchanov,Ralf Hofestaedt
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图书封面Titlebook: Bioinformatics of Genome Regulation and Structure;  Nikolay Kolchanov,Ralf Hofestaedt Book 2004 Springer Science+Business Media New York 20
影响因子.Bioinformatics of Genome Regulation and Structure. .covers: .-regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; .-large-scale genome analysis and functional annotation; .-gene structure detection and prediction; .-comparative and evolutionary genomics; .-computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure-function organization of genomic DNA, RNA, and proteins; .-gene networks, signal transduction pathways, and genetically controlled metabolic pathways: principles of organization, operation, and evolution; .-data warehousing, knowledge discovery and data mining; and, .-analysis of basic patterns of genome operation, organization, and evolution. .The data presented may be used while solving a wide range of problems, both basic and applied, in various directionsof molecular biology, molecular genetics, biotechnology, pharmacogenetics, pharmacology, and adjacent fields of medicine, veterinary, and agrobiology.
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Properties of Insertion Regions of , LTR Retrotransposonshosen as preferable for insertion. Preferential insertion of retrotransposons in the regions of host DNA displaying certain specific conformational and physicochemical properties may reflect the distinctions between the structures of DNA-recognizing domains of integrases of particular LTR retrotrans
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Sitecon—A Tool for Analysis of DNA Physicochemical and Conformational Properties: E2F/DP Transcription factor binding sites basing on a set of these conservative CDCPP determined are proposed in this work. To demonstrate implementation of the method, the binding sites of the heterodimeric complex E2F/DP were analyzed as an example The discovered specific CDCPP for a set of these binding sites refl
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b2181, II.2.3.3 Simple hydroxide chlorides,0 micro-insertions, and 211 indels. The change in complexity was found to be indicative of the type of repeat sequences involved in mediating the deletion/insertion event, which in turn provided pointers as to the possible pathways through which the mutations could have arisen.
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Key Element: O / Schlüsselelement: Oicted secondary structure stability and predicted expression level in the TSS region in some organisms. We assume that stability of the secondary structure in the region of translation start site can be an important factor in TSS recognition.
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