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Titlebook: Bioinformatics for Cancer Immunotherapy; Methods and Protocol Sebastian Boegel Book 2020 Springer Science+Business Media, LLC, part of Spri

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EPIC: A Tool to Estimate the Proportions of Different Cell Types from Bulk Gene Expression Data,ained from bulk samples containing a mixture of cell types. Knowledge of the proportions of these cell types is crucial as they are key determinants of the disease evolution and response to treatment. Moreover, heterogeneity in cell type proportions across samples is an important confounding factor
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Bioinformatics for Cancer Immunotherapy978-1-0716-0327-7Series ISSN 1064-3745 Series E-ISSN 1940-6029
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https://doi.org/10.1007/978-3-642-93460-5es. It is a Dockerized end-to-end pipeline that takes as input raw tumor/normal sequencing data. It is currently used in three clinical trials (NCT02721043, NCT03223103, and NCT03359239). In this chapter, we describe how to install and use OpenVax, as well as how to interpret the generated results.
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Kernspin-Tomographie in der Medizinogeneity in the tumors. Indeed, recent independent benchmark studies have revealed low concordance between different somatic mutation callers. Here, we describe .omatic .tation calling method using a .andom .orest (SMuRF), a portable ensemble method that combines the predictions and auxiliary featur
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