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Titlebook: Bioinformatics for Cancer Immunotherapy; Methods and Protocol Sebastian Boegel Book 2020 Springer Science+Business Media, LLC, part of Spri

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Rapid High-Resolution Typing of Class I HLA Genes by Nanopore Sequencing, nanopore sequencing. The method features a novel algorithm for candidate allele selection, followed by error correction through consensus building. Here, we describe the protocol of using Athlon packaged in a VirtualBox image for the above application.
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Computational Deconvolution of Tumor-Infiltrating Immune Components with Bulk Tumor Gene Expression immune cell types in the tumor microenvironment: B cell, CD4+ T cell, CD8+ T cell, neutrophil, macrophage, and dendritic cell. We further introduce its associated webserver for convenient, user-friendly analysis of tumor immune infiltrates across multiple cancer types.
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An Individualized Approach for Somatic Variant Discovery,Here, we describe an individualized approach for somatic variant discovery through the step-by-step usage of Personalized Reference Editor for Somatic Mutation discovery in cancer genomics (PRESM), a personalized reference editor for somatic mutation discovery in cancer genomes.
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HLApers: HLA Typing and Quantification of Expression with Personalized Index,eline which adapts widely used tools for analysis of standard RNA-seq data to infer HLA genotypes and estimate expression. By generating reliable expression estimates for each HLA allele that an individual carries, HLApers allows a better understanding of the relationship between HLA alleles and phenotypes manifested by an individual.
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