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Titlebook: Bioinformatics and Computational Biology Solutions Using R and Bioconductor; Robert Gentleman,Vincent J. Carey,Sandrine Dudoit Book 2005 S

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楼主: Pierce
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Versuchswerkstoffe und Probenherstellung,n analysis. Bioconductor provides tools for creating, distributing, and accessing annotation resources in ways that have been found effective in workflows for statistical analysis of microarray and other high-throughput assays.
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Quality Assessment of Affymetrix GeneChip Datahts obtained from fitting robust linear models to the probe level data can be used as a visual tool for identifying artifacts on GeneChip microarrays. Other output from the probe-level modeling tools provide summary plots that may be used to identify aberrant chips.
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Meta-data Resources and Tools in Bioconductorn analysis. Bioconductor provides tools for creating, distributing, and accessing annotation resources in ways that have been found effective in workflows for statistical analysis of microarray and other high-throughput assays.
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Browser-based Affymetrix Analysis and Annotation the pros and cons of using it versus the typical command line environment of R. Installation and configuration will be fully covered. Use of theWeb-based interface will be visually demonstrated. Finally, we will describe how to expand the interface by adding additional analysis modules.
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https://doi.org/10.1007/978-3-7091-3107-7 for preprocessing probe-level data stored in an . object into expression-level data stored in an . object. Because there are many competing methods for this preprocessing step, it is useful to have a way to assess the differences. In Bioconductor, this can be carried out using the affycomp package, which we discuss briefly.
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