Titlebook: Bioconductor Case Studies; Florian Hahne,Wolfgang Huber,Seth Falcon Book 2008 Springer-Verlag New York 2008 Annotation.Bioinformatics.Clus

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Kreativität im Kontext von New WorkIn this chapter we will cover some of the basic principles of finding differentially expressed genes. We cover nonspecific filtering, multiple testing, the moderated test statistics provided by the . package, and gene selection by ROC curves.

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Julia Sophie Haager,Tanja Gabriele BaudsonIn this chapter we demonstrate how to lay out and render graphs using tools from the . and . packages.

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The ALL Dataset,In this initial chapter we briefly describe the typical data preprocessing steps for a sample dataset that will be used in many of the following exercises.

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Two Color Arrays,In this case study, two RNA samples are compared to each other on 60 mer oligonucleotide microarrays using two-color labeling. The lab covers data import, visualization, exploration and normalization of the data, and the identification of differentially expressed genes.

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