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Titlebook: Biochemistry of Pulmonary Emphysema; C. Grassi,J. Travis,M. Luisetti Book 1992 Springer-Verlag London 1992 Alpha1-Proteinase Inhibitor.Lun

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Kostenrechnung in der Industriee USA, COPD caused more than 70,000 deaths in 1986 and more than 10,000,000 Americans suffered from the disease.. The association between severe α.protease inhibitor (α.PI) deficiency and emphysema has led to the hypothesis that an elastase-antielastase imbalance causes emphysema.. Human neutrophil
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Christian Ernst,Gerald Schenk,Peter Schuster% of the total protease inhibitory capacity in normal human serum.. In common with other members of the serine protease inhibitor superfamily,. the active inhibitory site of AAT is centred. around Ser.. Although it exhibits the capacity to inhibit a variety of proteases, including trypsin, chymotryp
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https://doi.org/10.1007/978-3-662-53508-0nic and organic particulates, gases, fumes and aerosols. To help defend itself, the lung has available a variety of mechanisms that can recruit inflammatory cells, particularly blood neutrophils. However while effective in killing microorganisms, the neutrophil is a dangerous “two-edged sword”, with
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Elastin and the Lung, is the principal component of the elastic fibre, which is a composite of the amorphous elastic protein and one or more microfibrillar components. Elastic fibres provide resiliency to numerous pulmonary structures including the alveolar wall, the bronchiolar interstitium, the medial layers of arteri
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