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Titlebook: Biochemistry of Halogenated Organic Compounds; Kenneth L. Kirk Book 1991 Springer Science+Business Media New York 1991 Amino acid.Nucleoti

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发表于 2025-3-21 19:35:31 | 显示全部楼层 |阅读模式
期刊全称Biochemistry of Halogenated Organic Compounds
影响因子2023Kenneth L. Kirk
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学科分类Biochemistry of the Elements
图书封面Titlebook: Biochemistry of Halogenated Organic Compounds;  Kenneth L. Kirk Book 1991 Springer Science+Business Media New York 1991 Amino acid.Nucleoti
影响因子Biochemistry of Halogenated Organic Compounds has been written as a general reference source for researchers in several related areas, including organic chemists, medicinal chemists, pharmacologists, toxicologists, and medical researchers. The development of halogenated compounds as medicinal agents and pharmacological tools and the fascinating biochemi­ cal processes that have been discovered and studied using these analogues have generated extremely active areas of research and an enormous volume of literature. Thus, halogenated organic compounds pervade every aspect of biochemistry, a fact made apparent by the numerous reviews and monographs available on individual topics-halogenated nucleosides, halogenated carbohydrates, and so forth. Given the quantity of material already written on these topics, some of which material is quite current, it might be asked whether a one-volume review of these subjects is useful, or possible. Having now completed this work, I feel the answer to both questions is an emphatic yes. There are fascinating stories to be related in each area, and, where appropriate, I have attempted to develop these topics . from a historical perspective. For example,
Pindex Book 1991
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Kostengünstig Entwickeln und Konstruiereniochemical behavior of these compounds. Examples to be reviewed in this chapter include the reaction of .-chloro- and .-bromoaldehydes with nucleic acid components and the use of .-halocarbonyl compounds as affinity labels. The presence of halogen also affects the chemistry of the neighboring carbon
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https://doi.org/10.1007/978-3-662-08196-9 and induction of labor, regulation of blood platelet aggregation, gastric acid secretion, stimulation of smooth muscle activity, and inflammation response. Since the initial isolation and identification of prostaglandins from sheep seminal vesicle glands and from human semen (PGF. and PGE, respecti
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Beeinflussung der Lebenslaufkosten,ided the initial example of the profound biological consequences of lethal synthesis (Chapter 1). The syntheses of fluorinated steroids by Fried and co-workers, based in part on the precedent provided by the altered biological activity of fluorocitrate, was a second development of historical proport
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Kostengünstig Entwickeln und Konstruierent (1972), Taylor (1972), and Taylor .. (1976)]. This research has been extended to many areas wherein halogenated carbohydrates have been used effectively as mechanistic probes and as leads for chemotherapeutic agents. For example, the successes realized in the use of halogenated sugars as component
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Kostenverantwortung der Produktentwickler,trate from fluoroacetate—a combination of effects may be seen, which can complicate interpretation of biological behavior. The situation becomes even more complex when the analogue can be incorporated into macromolecular systems essential to the functioning of the organism—the diversities of biologi
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Kostenverantwortung der Produktentwickler,ists, and halogenated amines that can affect neuronal function in other, less direct ways. The medicinal and pharmacological importance of both peripheral and central nervous system (CNS)-acting analogues will be reviewed. Of obvious importance are compounds that can modulate CNS functions, either t
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https://doi.org/10.1007/978-1-4757-4605-1Amino acid; Nucleotide; Pyrimidine; biochemistry; cancer; chemistry; research; steroids; ecotoxicology
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