Titlebook: Biochemical, Pharmacological, and Clinical Aspects of Nitric Oxide; Ben Avi Weissman,Nahum Allon,Shlomo Shapira Book 1995 Springer Science

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https://doi.org/10.1007/978-3-663-06743-6ar target proteins. In the the first part of this article, a brief synopsis will be given on enzymology of sGC related to its stimulation by NO, and in the second, more comprehensive part current knowledge about the mechanisms and regulation of NO biosynthesis will be reviewed.

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Biochemical, Pharmacological, and Clinical Aspects of Nitric Oxide978-1-4615-1903-4

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Nitric Oxide Synthase Inhibitors: Mechanism of Action and in Vivo Studiesmuscle (VSM) and endothelial cells has been shown to be a major hypotensive mediator in septic and cytokine-induced shock (7,12–15). Recent evidence also suggests iNOS-derived NO accounts in part for the tissue damage seen in inflammatory disorders including arthritis (16–18). Elucidation of these p