Titlebook: Biochemical Messengers; Hormones, neurotrans D. G. Hardie Book 1991 Springer Science+Business Media Dordrecht 1991

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,Cell Surface Receptors — Analysis and Identification,emed likely that only proteins could bind messengers with sufficiently high affinity and specificity to account for these observations. A protein which binds a first messenger, and is involved in mediating its biological effects, is known as a ..

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Signal Transduction by Nuclear Receptors,ulate gene expression at the level of transcription. While messengers acting at cell surface receptors can certainly affect transcription (e.g. Section 8.2.4), this only occurs as a secondary response to changes initiated in the cytoplasm.

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Anaerobic Chemotrophic Alkaliphilesthe first messengers are related to those common metabolites, and the metabolic pathways which interconvert them. The structure and synthesis of peptide messengers exhibits several features which are rather unique and sets them apart from the synthesis of other proteins, and they will be discussed separately at the end of the chapter.

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Journey to Diverse Microbial Worldsmetabolite (glucose), some of these vesicles fuse with the plasma membrane (Figures 5.1) to release their contents into the extracellular fluid (Figure 5.2). Exocytosis can also be visualized dramatically by electron microscopy of mast cells, which secrete the mediator histamine (see Figure 6.1).

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Journey to Diverse Microbial Worldsemed likely that only proteins could bind messengers with sufficiently high affinity and specificity to account for these observations. A protein which binds a first messenger, and is involved in mediating its biological effects, is known as a ..

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