| 期刊全称 | Bile Acids and Their Receptors | | 影响因子2023 | Stefano Fiorucci,Eleonora Distrutti | | 视频video | | | 发行地址 | Gives an overview on latest findings in the novel field of research of bile acids as signaling molecules.Offers a cross-country view of the functional role of bile acids as signaling molecules, virtua | | 学科分类 | Handbook of Experimental Pharmacology | | 图书封面 |  | | 影响因子 | This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the .de novo. bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis. | | Pindex | Book 2019 |
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发表于 2025-3-21 18:20:42
