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Titlebook: Beneficial Effects of Endotoxins; Alois Nowotny Book 1983 Springer Science+Business Media New York 1983 Colon.Lipid.Polysaccharid.bacteria

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Interleukin 1,ponses that involve macrophages. Specifically, IL 1 may be identical to the fever-producing substance endogenous pyrogen (Murphy ., 1980; Rosenwasser ., 1979), and appears to stimulate prostaglandin and collagenase release from synovial cells (Mizel ., 1981) and to release acute-phase reactants (Selinger ., 1980).
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Immunomodulatory Effects of Endotoxin,ame time or within a few days after antigen administration, but a depressed antibody response occurred if endotoxin preceded antigen. Thus, these early investigations demonstrated the dual nature of the effect of endotoxin on the immune response.
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Book 1983attributed to endotoxins. It is almost a generally applicable rule that both extremes in such fluctuations in the popularity of certain re­ search fields are unjustified. It is obvious that exaggerated expectations will lead to disappointments, and complete neglect of a once-exciting field is to be
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https://doi.org/10.1007/978-3-642-87076-7e Ages into our modern times, when “fever therapy” was applied to diseases as diverse as rheumatoid arthritis (Barsi, 1947), manic depression (Terry, 1939), headaches (Sutherland and Wolf, 1940), neurosyphilis (Favorite and Morgan, 1946), herpes zoster (Bernstein and Klotz, 1947), various eye and skin diseases (Tucker, 1946), and many others.
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1-jähriger Junge mit Ausschlag und Fiebernoculated intracerebrally in mice 75 min to 3. hr before an intracerebral challenge of 3–8 LD. of WS influenza virus decreased the direct neurotoxic effects of this virus. Typhoid vaccine was similarly effective. This protective effect lasted for about 7 days. No effect on viral multiplication in the brain was found.
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Induction of Interferon by Endotoxin,noculated intracerebrally in mice 75 min to 3. hr before an intracerebral challenge of 3–8 LD. of WS influenza virus decreased the direct neurotoxic effects of this virus. Typhoid vaccine was similarly effective. This protective effect lasted for about 7 days. No effect on viral multiplication in the brain was found.
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