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Titlebook: Beneficial Effects of Endotoxins; Alois Nowotny Book 1983 Springer Science+Business Media New York 1983 Colon.Lipid.Polysaccharid.bacteria

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期刊全称Beneficial Effects of Endotoxins
影响因子2023Alois Nowotny
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图书封面Titlebook: Beneficial Effects of Endotoxins;  Alois Nowotny Book 1983 Springer Science+Business Media New York 1983 Colon.Lipid.Polysaccharid.bacteria
影响因子The study of endotoxins has undergone cycles of enthusiastic research followed by neglect and revival again due to newly described biological effects attributed to endotoxins. It is almost a generally applicable rule that both extremes in such fluctuations in the popularity of certain re­ search fields are unjustified. It is obvious that exaggerated expectations will lead to disappointments, and complete neglect of a once-exciting field is to be followed by renewed attention, if the scientific basis of earlier interest was solid and remained so throughout. The healing ef­ fect of fever was praised as nature‘s blessed cure, until it was discov­ ered that it is caused by bacteria. When it became evident that by careful application one can arrive at therapeutic doses without intro­ ducing shock and hypotension, the era of fever therapy began. During this time, indiscriminate use of pyrogens was so widespread that the high expectations had to be followed by disillusionment. Since then, in­ terest in endotoxins experienced a few more oscillations, with varying wavelengths and amplitudes, the latest being triggered by the mitotic effect of endotoxin. This led to justified excitement amon
Pindex Book 1983
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Bakterien mit anderen Übertragungswegenighlight those aspects of the work with this strain that have dealt with the activation of lymphocytes by LPS, and to discuss in some detail the newer studies originating from the use of the C3H/HeJ mouse that have established that various proteins associated with the LPS in the outer membrane of gr
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Effect of LPS on Nonspecific Resistance to Bacterial Infections,endotoxin were found to be effective (see Cluff, 1971). However, depending upon the dose and route of administration, and upon the time interval prior to the infectious challenge, a transient increase in susceptibility to infection was also reported in the first papers (Rowley, 1956; Landy and Pille
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