Titlebook: Behavioral Neuroscience of Orexin/Hypocretin; Andrew J Lawrence,Luis de Lecea Book 2017 Springer International Publishing AG 2017 orexin/h

Intervention

刚毅

Moving Forward: Towards Innovative PracticeAcute stressors engage orexin neurons via direct projections from stress-sensitive brain regions. Orexin neurons, in turn, facilitate adaptive behavior via reciprocal connections as well as via direct projections to the hypophysiotropic neurons that coordinate the hypothalamic-pituitary-adrenal (HPA

Mechanics

https://doi.org/10.1057/9781137470348diction have major social and economic consequences and cause significant morbidity and mortality worldwide. Currently available therapeutics are inadequate, outlining the need for alternative treatments. Detailed knowledge of the neurocircuitry and brain chemistry responsible for aberrant behavior

ETHER

Moving Forward: Towards Innovative Practicethese neurons promotes conditioned morphine-seeking behavior. In the years since, contributions from many investigators have revealed roles for orexins in addiction for all drugs of abuse tested, but only under select circumstances. We recently proposed that orexins play a fundamentally unified role