Titlebook: Behavioral Neuroscience of Orexin/Hypocretin; Andrew J Lawrence,Luis de Lecea Book 2017 Springer International Publishing AG 2017 orexin/h

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A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?,these neurons promotes conditioned morphine-seeking behavior. In the years since, contributions from many investigators have revealed roles for orexins in addiction for all drugs of abuse tested, but only under select circumstances. We recently proposed that orexins play a fundamentally unified role

grounded

Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse, neurons send dense projections throughout the brain and recent observations suggest that both the intrinsic properties and the functional output of dopamine neurons are dependent on projection target and are subject to neuromodulatory influences. Lateral hypothalamic hypocretin (also termed orexin)

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Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse,ocretin peptides act at excitatory G. protein-coupled receptors and dynorphin acts at inhibitory G. protein-coupled receptors, which are both expressed on subpopulations of dopamine neurons. This review describes a role for neuromodulation of dopamine neurons and the influence on motivated behaviour in response to natural and drug rewards.

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What is Meant by ‘Internal Control’?d, and regulate various fundamental behaviors such as feeding, sleep, and wakefulness. Here we review how the zebrafish contributes to the study of the Hcrt neuronal system molecularly, anatomically, physiologically, and pathologically.

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