Titlebook: Bayesian Adaptive Design for Immunotherapy and Targeted Therapy; Haitao Pan,Ying Yuan Book 2023 Springer Nature Singapore Pte Ltd. 2023 Ad

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Model-Assisted Designs for Identifying the Optimal Biological Dose U-BOIN have the advantages of being simple to implement and meanwhile yielding competitive performances. Conducting the trial does not require complicated model estimation. The decision of dose transition can be easily made by looking up the pre-generated decision table. Examples and software are provided to illustrate BOIN12 and U-BOIN.