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Titlebook: Basic Immunology and Its Clinical Application; Mitsuru Matsumoto Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusiv

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0065-2598 ied to clinical use.Explores new methodologies, including im.This book overviews ongoing and upcoming clinical applications of basic immunology. Recent advances in our knowledge of immunology coupled with new technologies have aided in the development of efficient cancer immunotherapy, as well as th
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Novel Therapeutic Strategies to Combat HCC,rious ways for controlling physiological and pathological immune responses by targeting Treg cells. It is now envisaged that Treg cells as a “living drug” are able to achieve antigen-specific immune suppression of various immune responses and reestablish immunological self-tolerance in the clinic.
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MicroRNAs and Hepatocellular Carcinomaautoinflammatory and autoimmune diseases. Furthermore, some genes associated with these diseases promote endosomal TLR responses. Therefore, endosomal TLRs are promising therapeutic targets for TLR-mediated inflammatory diseases, and novel drugs targeting TLRs are being developed.
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Michel Modo,Thomas J. Meade,Ragai R. Mitry of PD-1 in 1992, a huge number of studies have been conducted to elucidate the function of PD-1. Herein, this paper provides an overview of PD-1 biological findings and sheds some light on the current technology for molecular imaging of PD-1.
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Autoinflammatory Diseases Due to Defects in Degradation or Transport of Intracellular Proteinsed common polygenic diseases. We have recently generated novel model mice in which complicated manifestations of human inborn errors of immunity affecting degradation or transport of intracellular proteins were recapitulated. Here, we review outline of these disorders, mainly based on the phenotype of the mutant mice we have generated.
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Endosomal Toll-Like Receptors as Therapeutic Targets for Autoimmune Diseasesautoinflammatory and autoimmune diseases. Furthermore, some genes associated with these diseases promote endosomal TLR responses. Therefore, endosomal TLRs are promising therapeutic targets for TLR-mediated inflammatory diseases, and novel drugs targeting TLRs are being developed.
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