Titlebook: Bacterial Pangenomics; Methods and Protocol Alessio Mengoni,Marco Galardini,Marco Fondi Book 2015 Springer Science+Business Media New York

变化

Mapping Contigs Using CONTIGuator,ncreasing number of bacterial species having more than one strain sequenced, thus facilitating the annotation process. On the other hand, many genomic sequences are now left in the “draft” status, as a series of contigs, mainly for the labor-intensive finishing task. As a result, many genomic analys

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Defining Orthologs and Pangenome Size Metrics,asingly more genomes from microbes belonging to the same taxonomic unit. Eventually, this led to the concept of ., that is, the entire set of genes present in a group of representatives of the same genus/species, which, in turn, can be divided into ., defined as the set of those genes present in all

Expertise

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Genome-Scale Metabolic Network Reconstruction,oit new usable substances of microbial origin. Computational modeling and in silico simulations are powerful tools in this context since they allow the exploration and a deeper understanding of bacterial metabolic circuits. Many approaches exist to quantitatively simulate chemical reaction fluxes wi

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Inordinate

Genome-Wide Detection of Selection and Other Evolutionary Forces,ions occur frequently during the long-term pathogen–host evolutionary arms race, and individual mutation beneficial for the fitness can be fixed preferentially. Many recent comparative genomics studies have pointed out the importance of selective forces in the molecular evolution of bacterial pathog

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The Integrated Microbial Genome Resource of Analysis,arative analysis of microbial genomes and metagenomes. IMG has been developed by the US Department of Energy (DOE)-Joint Genome Institute (JGI). IMG platform contains both draft and complete genomes, sequenced by Joint Genome Institute and other public and available genomes. Genomes of strains belon

Spinal-Fusion

1064-3745 ation advice from the experts.Bacterial genomics is a mature research interdisciplinary field, which is approached by ecologists, geneticists, bacteriologists, molecular biologists and evolutionary biologists working in medical, industrial and basic science. Thanks to the large diffusion of bacteria

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