Titlebook: Bacterial Multidrug Exporters; Methods and Protocol Akihito Yamaguchi,Kunihiko Nishino Book 2018 Springer Science+Business Media, LLC 2018

JADE

书目名称Bacterial Multidrug Exporters影响因子(影响力)




书目名称Bacterial Multidrug Exporters影响因子(影响力)学科排名




书目名称Bacterial Multidrug Exporters网络公开度




书目名称Bacterial Multidrug Exporters网络公开度学科排名




书目名称Bacterial Multidrug Exporters被引频次




书目名称Bacterial Multidrug Exporters被引频次学科排名




书目名称Bacterial Multidrug Exporters年度引用




书目名称Bacterial Multidrug Exporters年度引用学科排名




书目名称Bacterial Multidrug Exporters读者反馈




书目名称Bacterial Multidrug Exporters读者反馈学科排名

刺激

Crystallographic Analysis of Drug and Inhibitor-Binding Structure of RND-Type Multidrug Exporter AcrMurakami et al., Nature 443:173–179, 2006; Nakashima et al., Nature 480:565–569, 2011; Nakashima et al., Nature 500:120–126, 2013). Analyses revealed the existence of a specific mechanism to recognize numerous substrates that the multisite binding is the base of multidrug recognition rather than ind

BIBLE

Generation of Conformation-Specific Antibody Fragments for Crystallization of the Multidrug Resistannizing the native conformation of a major facilitator superfamily (MFS)-type MDR transporter MdfA from .. We confirmed that the use of Fab fragments was efficient for stabilization of MdfA and improvement of its crystallization properties.

infelicitous

Covalently Linked Trimers of RND (Resistance-Nodulation-Division) Efflux Transporters to Study Theirnvolved in proton relay, or in “real time” by using a protein in which one protomer contains two Cys residues on both sides of the large cleft in the periplasmic domain and then by rapidly inactivating this protomer with a methanethiosulfonate cross-linker.

删减

Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transportersmics simulations and in silico free energy estimations can all together give precious insights into the processes of recognition and extrusion of substrates, as well as on the possible inhibition strategies.

胆汁

粗鲁的人

https://doi.org/10.1007/978-3-658-19558-8nizing the native conformation of a major facilitator superfamily (MFS)-type MDR transporter MdfA from .. We confirmed that the use of Fab fragments was efficient for stabilization of MdfA and improvement of its crystallization properties.

脆弱带来

轻快来事

https://doi.org/10.1007/978-3-476-05869-0mics simulations and in silico free energy estimations can all together give precious insights into the processes of recognition and extrusion of substrates, as well as on the possible inhibition strategies.

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