Titlebook: Bacterial Capsules; Klaus Jann,Barbara Jann Conference proceedings 1990 The Editor(s) (if applicable) and The Author(s), under exclusive l

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https://doi.org/10.1007/978-3-642-74694-9Antigene; Antigenes; Gene organisation; Genorganisation; Infection; Infektionen; Kapselpolysaccharide; Poly

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Conference proceedings 1990ytes. This bacterial self protection is brought about by encapsulation. Bacterial capsules thus enable the pathogenic bacteria to survive in the host by counter­ action or evasion of the nonspecific host defense in the early pre immune phase of an infection. It is only in the late immune phase of th

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Capsular Polysaccharides as Vaccine Candidates,neumococcal polysaccharide vaccines were able to provide type-specific protection in humans against the acquisition of pneumococcal infection (M.L. et al. 1945). However, at this time the phenomenal success of antibiotic therapy in the treatment of bacterial infections caused a lengthy hiatus in the further development of polysaccharide vaccines.

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Structure and Biosynthesis of the Capsular Antigens of ,,s. This layer consists of proteins, lipoproteins, phospholipids, and lipopolysaccharides (LPSs). LPSs of smooth wild-type bacteria, consisting . lipid A, core, and O-specific polysaccharide, are O antigens and those of rough mutants consisting only of lipid A and core are R antigens (J.and W.1975; J

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