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Titlebook: BCL‑2 Protein Family; Essential Regulators Claudio Hetz Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive license

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期刊全称BCL‑2 Protein Family
期刊简称Essential Regulators
影响因子2023Claudio Hetz
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发行地址Focusses on the potential therapeutic benefits of targeting apoptosis pathways in the context of human disease.Provides an overview of the emerging roles of BCL-2 family members in different physiolog
图书封面Titlebook: BCL‑2 Protein Family; Essential Regulators Claudio Hetz Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive license
影响因子In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.
Pindex Book 2010
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,Later Nyāya Logic: Computational Aspects,ells have evolved a highly integrated network of control mechanisms, including positive and negative feedback loops, to safeguard homeostasis in face of a wide range of stimuli. Such control mechanisms ultimately orchestrate cell death, division and repair in a manner concordant with cellular energy
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Logical Proofs in the , of Somānandaeins is a group of evolutionarily conserved regulators of cell death that comprises both anti- and pro-apoptotic members, that operate at the mitochondrial membrane to control caspase activation. Different BCL-2-related proteins are also located in the endoplasmic reticulum (ER), where important rol
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General Introduction to Buddhist Logic Stringent regulation of redox and calcium homeostasis is paramount, failure of which leads accumulation of unfolded and aggregating proteins resulting in a condition known as ER stress. Eukaryotic cells deal with ER stress by eliciting the unfolded protein response (UPR). This pathway splits into t
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Grace A. Mucci,Lilibeth R. Tornoulminates in the release of cytochrome c from the organelle in the cytoplasm, where it is required for the activation of effector caspases. The complete release of cytochrome c is the result of the combined action of proapoptotic BCL-2 family members and of changes in the complex morphology and ultr
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