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Titlebook: Applied Physiology to Reduce Ventilator Induced Lung Injury; Clinical Application Gary F. Nieman,Nader M. Habashi Book 2024 The Editor(s) (

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发表于 2025-3-26 23:04:12 | 显示全部楼层
The Acutely Injured Lung Becomes Time/Press Dependent,ress multiplication that cause both atelectrauma and volutrauma. Unstable alveoli result in repetitive alveolar collapse and expansion (RACE), which is the mechanism of atelectrauma. If RACE is allowed to continue unchecked, the excessive shear or “peeling” stress in collapsed alveoli and small airw
发表于 2025-3-27 03:02:52 | 显示全部楼层
Applied Physiologic Analysis of Clinically Tested Protective Ventilation Strategies,l lung (referred to as the “baby lung”) by employing low tidal volume (V.) and low plateau pressure (Pplat). Positive end-expiratory pressure (PEEP) is set based on oxygenation to prevent further collapse of lung tissue and mitigate the risk of slipping into the VILI vortex, (Acute Respiratory Distr
发表于 2025-3-27 06:20:09 | 显示全部楼层
,It’s Not the Wand; It’s the Wizard: It’s Not Just the Mode but the Method Used to Set and Adjust th (MB.). The goal is to minimize lung pathophysiology predisposing the lung to secondary VILI. The MB. encompasses airway volumes, pressures, flows, rates, and the timing of their application during inspiration and expiration. The chapters will scrutinize highly specific methods for setting and adjus
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Novel Time-Controlled Adaptive Ventilation Method to Minimize VILI,proach (SLA) method to set and adjust the airway pressure release ventilation (APRV) mode. This method represents a paradigm shift in lung-protective mechanical ventilation, designed to immediately stabilize alveoli and prevent progressive loss of EELV, thereby removing the lungs’ progression into t
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,Adaptive Dynamic Sub-tidal Ventilation (ADSV ,): Lung Protection by Millisecond Adjustments in Gas eal solution is a ventilator technology that responds to changes in lung pathophysiology at the micro-level and considers global lung elastance and resistance. The innovative approach of Adaptive Dynamic Sub-tidal Ventilation (ADSV technology) offers a promising solution to ventilate the heterogeneo
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Elizabeth C. Oesterle,Jennifer S. Stonebly high mortality rate resistant to standard treatments. This surge has underscored the limitations of traditionally accepted standards of care, highlighting the crucial need to deepen our understanding of ARDS pathophysiology. The urgency for personalized, protective mechanical ventilation strateg
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https://doi.org/10.1007/b138721ese initial lesions serve as focal points, facilitating the rapid propagation of ventilator-induced lung injury (VILI) throughout the pulmonary tissue. The fundamental stages in the pathogenesis of ALI include Endothelial Leakage → Surfactant Deactivation → Alveolar Edema → Repetitive Alveolar Colla
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