Titlebook: A Pragmatic Approach to Conceptualization of Health and Disease; Maartje Schermer,Nicholas Binney Book‘‘‘‘‘‘‘‘ 2024 The Editor(s) (if appl

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,Cultivate Your Own Garden—Some Reflections on Martin Kusch’s Overview of Relativism in Medical Hist civic communities of their opponents from time to time (Kant 1929). This process of construction and destruction continues afterwards. Although scepticism and relativism are two different philosophical positions, relativists may show enough similarities with sceptics to count them among Kantian nom

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Is There an Epistemic Role for History in Medicine? Thinking About Thyroid Cancer,hyroid cancer researchers have suggested that knowledge of the history of thyroid cancer would have helped prevent this problem. Their intuition is that history has an epistemic role to play in justifying contemporary medical knowledge. This conflicts with an opposing intuition that history is irrel

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A Plea for More History, therefore justifying medical knowledge and practice. From my perspective as a medical historian, Binney’s programmatic text raises three questions: (1) Is this epistemic role for history important?; (2) Is Binney’s argument convincing?; (3) How can a plea for history . so ahistorical, or more posit

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Scope Validity in Medicine,texts of research and application. Drawing on examples of extrapolating results from animal models to human patient populations, the chapter proposes a shift in perspective away from idealized target constructs that can be hit and towards concrete practices of operationalization that render diseases

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,Scope Validity in Medicine: An Asset to the Epidemiologist’s Armoury,medicine. This lack of transportability may improve by focus on ‘scope validity’: the extent to which an experimental target matches the intended application. Positioned amidst construct validity and external validity, more awareness and better articulation of the scope of preclinical investigations

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,The Biomarkerization of Alzheimer’s Disease: From (Early) Diagnosis to Anticipation?,ersy about the desirability of early diagnosis. Biomarkers’ role in early diagnosis and definition of disease, as well as the controversies this raises, are particularly noticeable in the domain of Alzheimer’s disease (AD). This chapter analyses how the introduction of biomarkers in the AD field has

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Biomarking Life,ers make disease more physiological and anticipatory and medicine more person centred may need more research. Clearly, biomarkers can decouple medicine and healthcare from what matters to people (such as pain, dysfunction, and suffering), reducing the moral relevance of medicine. Hence, putting biom

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