Titlebook: Autophagy in tumor and tumor microenvironment; Sujit Kumar Bhutia Book 2020 Springer Nature Singapore Pte Ltd. 2020 Autophagy.Cancer.Stem

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Great Powers, Weak States, and Insurgencyhe genes of stage-specific regulation of autophagy could be a novel approach for the directive suppression and prevention of cancer. Moreover, the endocytosis–autophagy crosstalk gives an edge to develop drugs which specifically acts upon the cancer cells and modulate the autophagy process. In addit

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miRNAs and Its Regulatory Role on Autophagy in Tumor Microenvironment,nscriptionally. They control many important biological pathways including autophagic response in cancer. Their expression also gets dysregulated during different stages of cancer and thus gives a promising window of their utility as an attractive target during tumor therapy. Therefore, considering t

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Exploring the Metabolic Implications of Autophagy Modulation in Tumor Microenvironment,point of therapy. Specificity and efficacy issues of autophagy-dependent cell death remain largely uncertain. This brings us to focus on the controversies and lacunas in the understanding of cell death and autophagy. The tumor microenvironment (TME) is regarded as a bed of metabolic cascade that ens

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Mitophagy and Reverse Warburg Effect: Metabolic Compartmentalization of Tumor Microenvironment,s evidenced by the higher expression of autophagic and mitophagic signature molecules. Moreover, caveolin-1 and hypoxia-inducible factor-1α play a fundamental role in governing the mitophagy-mediated occurrence of ‘reverse Warburg effect’. To the surprise, cancer stem cell also follows the same stra

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