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Titlebook: Autophagy in tumor and tumor microenvironment; Sujit Kumar Bhutia Book 2020 Springer Nature Singapore Pte Ltd. 2020 Autophagy.Cancer.Stem

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发表于 2025-3-21 17:51:02 | 显示全部楼层 |阅读模式
期刊全称Autophagy in tumor and tumor microenvironment
影响因子2023Sujit Kumar Bhutia
视频video
发行地址Reviews the paradoxical roles of autophagy in tumor suppression and tumor promotion.Summarizes the physiological function of autophagy in tumorigenesis, metastasis, targeted-therapy, and drug resistan
图书封面Titlebook: Autophagy in tumor and tumor microenvironment;  Sujit Kumar Bhutia Book 2020 Springer Nature Singapore Pte Ltd. 2020 Autophagy.Cancer.Stem
影响因子.This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies.. .The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers avaluable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology..
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发表于 2025-3-21 22:57:01 | 显示全部楼层
https://doi.org/10.1007/978-1-349-10075-0radation of cytoplasmic components, causing “autophagic cell death.” Autophagy can also rescue cancer cells from apoptosis by modulating stress levels, determining cancer cell fate. However, the molecular signals driving the cell toward either autophagy or apoptosis remain largely unknown. Therefore
发表于 2025-3-22 01:45:59 | 显示全部楼层
https://doi.org/10.1007/978-1-349-10075-0provide comprehensive insights into the underlying mechanisms involved in the molecular crosstalk between DDR and autophagy, which differentially regulate cancer cell fate in response to DNA damaging chemotherapeutics and radiotherapeutics or chemotherapy and radiotherapy.
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发表于 2025-3-22 12:17:18 | 显示全部楼层
https://doi.org/10.1007/978-1-349-10075-0point of therapy. Specificity and efficacy issues of autophagy-dependent cell death remain largely uncertain. This brings us to focus on the controversies and lacunas in the understanding of cell death and autophagy. The tumor microenvironment (TME) is regarded as a bed of metabolic cascade that ens
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Is Russia a Great Power in Asia?,nsatory mitochondrial biogenesis may also give rise to malfunction of mitochondria and lead to mitophagic cell death. Similarly, triggering the biogenesis of new mitochondria has been advantageous, although the hyperactivity of which may lead to higher oxygen consumption and oxidative stress. Theref
发表于 2025-3-22 21:17:24 | 显示全部楼层
The Shifting Territorial Logic of Hierarchy,mber of study spotlights the context-dependent role of autophagy in cancer immunity: it can activate the anti-tumor immunity by sustaining the integrity of the immune cells; however, it can also help the tumor cells to bypass the immune checkpoints by constraining the immune cell functions during hy
发表于 2025-3-23 03:35:28 | 显示全部楼层
https://doi.org/10.1007/978-3-319-94096-0e autophagy plays roles in both tumor suppression and promotion. Further detailed examination of autophagy in cancer is required to understand how an increased function of autophagy in the tumor microenvironment, stemness, migration and invasion, dormancy, and drug resistance could be tweaked for en
发表于 2025-3-23 07:06:50 | 显示全部楼层
Order (and Disorder) in World Order, evidence for autophagy-related genes and proteins as reliable markers of disease severity and prognosis and analyse the efficacy of autophagy manipulation in improving cancer treatment outcomes and circumventing chemoresistance.
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