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Titlebook: Autoimmunity; Methods and Protocol Andras Perl Book 20041st edition Humana Press 2004

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期刊全称Autoimmunity
期刊简称Methods and Protocol
影响因子2023Andras Perl
视频video
发行地址Includes supplementary material:
学科分类Methods in Molecular Medicine
图书封面Titlebook: Autoimmunity; Methods and Protocol Andras Perl Book 20041st edition Humana Press 2004
影响因子“Research is to see what everybody else has seen, and to think what nobody else has thought. ” — Albert Szentgyörgyi Autoimmunity: Methods and Protocols is intended to serve as a ready-to-use guide to establish and interrogate human and animal models of autoimmune diseases. The first chapter, “Pathogenesis and Spectrum of Autoimmunity,” discusses major hypotheses driving this most tantalizing area of research since Paul Ehrlich proposed the concept of autoimmunity in 1900. Considering the great diversity and ever-changing spectrum of autoimmunity, it has not been possible to include models and experimental protocols for each known disorder. Rather, several chapters have been devoted to the most prevalent and complex diseases, such as rheumatoid arthritis, systemic lupus erythematosus, insulin-dependent diabetes mellitus, and multiple sclerosis. The chapters are contributed by laboratories actively using the models presented. Each chapter contains an introductory section that discusses the relevance of the model for a particular disease and for autoimmunity in general. Part I contains methods and protocols to assess immunological and biochemical pathways relevant for disease pathoge
Pindex Book 20041st edition
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书目名称Autoimmunity影响因子(影响力)




书目名称Autoimmunity影响因子(影响力)学科排名




书目名称Autoimmunity网络公开度




书目名称Autoimmunity网络公开度学科排名




书目名称Autoimmunity被引频次




书目名称Autoimmunity被引频次学科排名




书目名称Autoimmunity年度引用




书目名称Autoimmunity年度引用学科排名




书目名称Autoimmunity读者反馈




书目名称Autoimmunity读者反馈学科排名




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Die Bestimmung gesteinsbildender Minerale system, tolerance mechanisms develop that prevent or inhibit potentially harmful reactivities to self-antigens. Autoreactive B and T cells that are generated during immune responses are eliminated by apoptosis in the thymus, lymph nodes, or peripheral circulation or are actively suppressed by regul
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Erfahrungen beim Ersten Aufstau,as led to the characterization of a signaling defect, involving protein kinase A (PKA), leading to abnormal T-cell effector functions in SLE. PKA is a component of the adenylyl cyclase/cyclic adenosine monophosphate/PKA (AC/cAMP/PKA) pathway, a principal signal transduction system in T cells. The ai
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Erfahrungen beim Ersten Aufstau,n, or death of cells of the immune system are dependent on controlled reactive oxygen intermediate (ROI) production and ATP synthesis in mitochondria. The mitochondrial transmembrane potential (ΔΨ.) reflects the energy stored in the electrochemical gradient across the inner mitochondrial membrane, w
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