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Titlebook: Autoimmune Reactions; Sudhir Paul Book 1999 Springer Science+Business Media New York 1999 Antigen.antigen presentation.autoimmune disease.

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The Role of Exogenous Stimulation in Pathogenesis of Autoimmune Diseases,ted from the repertoire. In the thymus, a process known as negative selection appears to result in deletion of T-cells bearing receptors with high affinity for self-antigens .. In the fetal liver and bone marrow, a similar process deletes the emerging B-cells bearing an Ig receptor specific for cellular antigens ..
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Cellular Entry and Nuclear Localization of Anti-DNA Antibodies,tion in various tissues (along with other autoantibodies) initiates an inflammatory response that frequently leads to organ failure despite intensive immunosup-pressive therapy .. Nevertheless, the features that distinguish pathogenic from nonpathogenic autoantibodies have been the subject of considerable debate.
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T-Cell Antigen Receptor Repertoire in Rheumatoid Arthritis,-cells . in a perivascular location. Moreover, T-cell depleting therapy in RA, and in animal models of RA, can be beneficial. Finally, genetic susceptibility to RA is strikingly associated with certain MHC class II alleles which may either control peptide presentation to T-cells or influence T-cell repertoires during thymic maturation.
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Book 1999urrent limitations as unifying explanations of the diseases described. The book illustrates the type of thinking and research that should eventually permit development of palliatives and cures for autoimmune diseases...
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nd their current limitations as unifying explanations of the diseases described. The book illustrates the type of thinking and research that should eventually permit development of palliatives and cures for autoimmune diseases...978-1-4612-7215-1978-1-4612-1610-0
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