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Titlebook: Autoimmune Liver Diseases; Perspectives from Ja Hiromasa Ohira Book 2014 Springer Japan 2014 AIH.PBC.autoimmune hepatitis.primary biliary c

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发表于 2025-3-21 18:26:45 | 显示全部楼层 |阅读模式
期刊全称Autoimmune Liver Diseases
期刊简称Perspectives from Ja
影响因子2023Hiromasa Ohira
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发行地址Based on Japanese research findings in autoimmune liver diseases.Explains how Japanese patients with autoimmune hepatitis form a unique disease population as a result of their genetic background.Prese
图书封面Titlebook: Autoimmune Liver Diseases; Perspectives from Ja Hiromasa Ohira Book 2014 Springer Japan 2014 AIH.PBC.autoimmune hepatitis.primary biliary c
影响因子.Autoimmune Liver Diseases. summarizes the recent high-impact research and clinical findings obtained in Japan in the study and treatment of autoimmune liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, the other with PBC. .AIH in Japanese patients creates a unique disease population, as its clinical features are different from those of Western patients resulting from the different genetic background of the two patient populations. Also, mouse models of neonatal thymectomy-PD-1 knockout mice, clinical analyses of acute hepatitis-like manifestations, and research findings on IgG4-related autoimmune hepatitis have been reported in Japan and are included in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the d
Pindex Book 2014
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Histological Findings of Autoimmune Hepatitisical interaction of lymphocytes and hepatocytes, is noted but is sometimes difficult to evaluate. In addition to classical AIH, showing chronic active hepatitis, some AIH patients show a clinically acute hepatitis-like clinical course. These patients have mostly acute exacerbation from chronic activ
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Management Strategies for Autoimmune Hepatitis Treatment Nonrespondersfects. Therefore, an investigation of the pathological conditions associated with this disease, such as severity, complications, and age, as well as the use of immunosuppressant, AZA therapy, and other treatments, is warranted for treatment-resistant cases. The applicability of liver transplantation
发表于 2025-3-22 20:06:54 | 显示全部楼层
Nonalcoholic Steatohepatitis-Autoimmune Hepatitis Overlapd AIH are wide and thus, clinical findings of both NASH and AIH can coexist. NASH-AIH overlap should be clinically treated as coexisting AIH and NASH regardless of whether or not each is an independent disease entity.
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Animal Models for Primary Biliary Cirrhosisd from exogenous costimulatory immunoreceptor-conjugated immunoglobulin, i.e., cytotoxic T lymphocyte antigen 4 (CTLA-4)-Ig, was quite efficient to improve developed cholangitis in 2OA-BSA-immunized mice. These results highlighted the pivotal roles of T cells, especially CD8. T cells, the regulatory
发表于 2025-3-23 07:44:17 | 显示全部楼层
Epidemiology and Natural History in Japan by liver disease has decreased. The 5-year survival rates were 97.9 and 80.3 %, the 10-year survival rate 93.7 and 66.7 %, and the 20-year survival rate 84.2 and 52.1 %, respectively, showing significant differences among the groups (. < 0.0001). As results of examining changes in survival rate of
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