期刊全称 | Autoimmune Liver Diseases | 期刊简称 | Perspectives from Ja | 影响因子2023 | Hiromasa Ohira | 视频video | | 发行地址 | Based on Japanese research findings in autoimmune liver diseases.Explains how Japanese patients with autoimmune hepatitis form a unique disease population as a result of their genetic background.Prese | 图书封面 |  | 影响因子 | .Autoimmune Liver Diseases. summarizes the recent high-impact research and clinical findings obtained in Japan in the study and treatment of autoimmune liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, the other with PBC. .AIH in Japanese patients creates a unique disease population, as its clinical features are different from those of Western patients resulting from the different genetic background of the two patient populations. Also, mouse models of neonatal thymectomy-PD-1 knockout mice, clinical analyses of acute hepatitis-like manifestations, and research findings on IgG4-related autoimmune hepatitis have been reported in Japan and are included in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the d | Pindex | Book 2014 |
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