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Titlebook: Auto-Inflammatory Syndromes; Pathophysiology, Dia Petros Efthimiou Book 2019 Springer Nature Switzerland AG 2019 auto-inflammatory syndrome

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Length-Based and Quotient Attacksxcess secretion of interleukin 1. CAPS is characterized by systemic and organ inflammation baring the risk of irreversible damage including sensorineural hearing loss, renal failure, hydrocephalus, and skeletal deformities. International efforts have advanced our understanding of the disease mechani
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Background on Computational Complexitytion of endogenous nucleic acids, excessive sensitivity or activity of DNA/RNA sensors, and the dysregulation of type I IFN pathway have been identified as the main contributors to excessive type I IFN signaling in this setting. Chilblain-like lesions, central nervous system calcifications, intersti
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Background on Combinatorial Group Theorymatory disease characterized by periodic fever, dermatitis, arthritis, and swelling of the distal extremities, as well as gastrointestinal and sicca-like symptoms. The disorder is associated with specific . variants.
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Asymptotically Dominant Propertiesiven condition characterized by chronic, multiorganic inflammatory involvement. Typical clinical features including young age at presentation, fever, neutrophilic skin lesions, synovitis, serositis, organomegaly, as well as increased risk of amyloidosis are reminiscent of (and may mimic) certain mon
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