Titlebook: Attempts to Understand Metastasis Formation II; Regulatory Factors Ursula Günthert,Walter Birchmeier Book 1996 The Editor(s) (if applicable

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Barriers to Participation in AETnes that contribute to carcinoma formation and progression have been identified. The most frequent mutations found in carcinomas include activating mutations in the . family of genes, mutations that interfere with the function of p53, and amplification or overexpression of genes encoding tyrosine ki

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Vertical Axis: Volume of Participationires the invasion of surrounding normal tissue and crossing of vascular and/or lymphatic boundaries (N. 1988; F. 1990) and it has been suggested that motility of individual cells or groups of cells at the leading edge of a tumor protrusion might be responsible for such invasive movement (S. and W. 1

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Body Images in Youth Cultural Mediassels, survival in the blood stream, extravasation, and growth of secondary tumors in distant organs (L. et al. 1983, 1991; S. 1985; N. 1988; H. and S. 1992). Many proteins have been identified which may play a role in the different stages of tumor progression and metastasis and which distinguish me

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,Formations of Style and Affiliation,l growth continues in tumors whereas normal cells for the most part cease dividing and retain a diploid amount of DNA suggests that the controls regulating the normal cell cycle have failed to function in the tumor cell. In recent years the biochemical mechanisms underlying the transitions through t

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Material Artifacts as Competence Markersneoplastic development (Z. et al. 1993), normal development and differentiation (D. et al. 1988; B. et al. 1988, W. et al. 1990; Y. et al. 1994), proliferation (K. et al. 1992; O. et al. 1994), and cell motility (K. et al. 1993). All . genes encode the metabolic enzyme nucleoside diphosphate kinase

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Current Topics in Microbiology and Immunologyhttp://image.papertrans.cn/b/image/164880.jpg