Titlebook: Atlas of Hepatocellular Carcinoma Pathology; Haeryoung Kim,Wei-Qiang Leow,Anthony Wing-Hung Cha Book 2022 The Editor(s) (if applicable) an

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Macrotrabecular-Massive Hepatocellular Carcinoma,rvival and early recurrence. We cover the salient histological features and the utility of some immunohistochemical markers. Amongst the molecular aberrations, FGF19 amplification is potentially druggable.

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Hepatocellular Carcinoma with Cytokeratin 19 Expression,nstrated in a subset of hepatocellular carcinomas (HCCs). Also known as “HCC with stemness-related marker expression”, CK19-expressing HCC is not recognised as a histopathological variant of HCC in the current WHO classification; however, there is accumulating data on the aggressive clinicopathologi

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Tumour Staging for Hepatocellular Carcinoma,nical decision-making to guide patient management. More than 20 staging systems have been developed for hepatocellular carcinoma (HCC) due to the complexity and heterogeneity of the disease. The number of staging systems is expected to expand continuously. Each system has its own strengths and short

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Differential Diagnoses of Hepatocellular Carcinoma,ial diagnoses should be considered before issuing a malignant diagnosis of HCC. Differential diagnoses of HCC could be formulated by the pathological nature of the lesion and the status of the non-tumourous liver. This chapter provides a brief non-exhaustive overview of various differential diagnose

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Possibility and Impossibility Results for Encryption and Commitment Secure under Selective Opening precursors which usually have no or reduced biological activity. The conversion to the mature secreted forms of the peptides involves limited proteolysis and frequently post-translational modifications to individual amino acid residues. Determination of a biosynthetic pathway requires a collaborati