Titlebook: Atlas of Graft-versus-Host Disease; Approaches to Diagno Jonathan A. Cotliar Book 2017 Springer International Publishing AG 2017 GVHD.Graft

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Diagnosis, Staging, and Treatment of Chronic Graft-Versus-Host Disease, cell transplantation (HSCT), and the incidence of cGVHD continues to rise [1]. Evolving transplantation practices, including the use of mobilized peripheral stem cells, transplantation of older recipients, and more frequent use of mismatched transplants, may explain the occurrence of this vexing problem.

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Nimol Thuon,Jun Du,Jianshu ZhangThe procedure involves transfusion of multipotent hematopoietic stem cells derived from bone marrow, peripheral blood, or umbilical cord blood from a donor, usually matched in human leukocyte antigens (HLA). Immediately prior to HSCT, patients receive conditioning chemoradiotherapy to eliminate unde

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https://doi.org/10.1007/978-3-031-21648-0ll transplant (HSCT) [1, 2].Chronic GVHD and its associated complications result in increased resource utilization, poor quality of life parameters, and decreased overall survival in patients. Early detection and appropriate intervention will help in improving long-term outcomes of HCT patients. Det

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Ricardo P. Garay,Philippe Meyeral sites share similarities in symptoms, clinical signs, and histopathologic features. Early and accurate diagnosis of GVHD, in conjunction with timely intervention, is key to minimizing discomfort and unnecessary medication exposure, and to preventing irreversible organ damage and functional defici

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Ricardo P. Garay,Philippe Meyerhis entity in a timely manner is often hindered by clinical and histopathologic mimickers, such as drug hypersensitivity reactions, viral exanthema, and toxic erythema of chemotherapy. Microscopic findings in acute and chronic cutaneous GVHD are reviewed here, as are features of other entities in th