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Titlebook: Atherogenesis and Aging; Sandra R. Bates,Edwin C. Gangloff Book 1987 Springler-Verlag New York Inc. 1987 cardiovascular.endothelium.metabo

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The Pathogenesis of Atherosclerosis: Myths and Established Facts About Its Relationship to Aging development of the atherosclerotic plaque as observed at autopsy with the age of the individual and with selected disease processes such as hypertension, diabetes and hyperlipidemia. This approach has led to many valuable observations including the concept that atherogenesis starts relatively early
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Perspectives in the Biology of Agingown about the biology of aging. Historically, and even in the modem era, gerontology has attracted more than its share of scientists of questionable talent, motives and integrity. As a result, outstanding investigators who have been interested in aging have shied away from research in this important
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Effect of Age on Atherosclerosis Progression in Nonhuman Primatesassociation between age and atherosclerosis progression, it is surprising that so few experimental studies have been done to assess age differences in susceptibility to diet-induced atherosclerosis. In this report, we review briefly our own experience with age differences in atherogenesis among the
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Aging, Lipoprotein Metabolism, and Atherosclerosis: A Clinical Conundrumsm, and atherosclerosis indeed present a conundrum of significant proportions to clinicians and basic scientists alike. As with much gerontological research, this dilemma derives from the inextricable relationship between aging and the passage of time. Four models might be proposed to describe the r
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Alterations in the Arterial Wall with Agingpment of atherosclerosis. Much of what has been considered falls into the category of “risk factors” that are present in the blood, such as changes in plasma lipoproteins, blood pressure, hormones, etc. A variety of studies have indicated that the commonly accepted risk factors can account for only
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Cultured Endothelial Cells as a Model for Aging and Atherogenesisstrategic position, the endothelium plays a key role in an organism’s function and survival (1). Also, almost every mechanism proposed for atherogenesis involves the endothelium in some way (1,2). In 1954, Rudolf Altschul brought a finer focus to the cliche about arteries and aging by stating that:
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