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Titlebook: Asthma: Targeted Biological Therapies; Girolamo Pelaia,Alessandro Vatrella,Rosario Masell Book 2017 Springer International Publishing Swit

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https://doi.org/10.1007/978-3-8348-9214-0) (Fig. 2.1). In addition to being driven by adaptive immune responses, airway eosinophilia can also arise from innate immune mechanisms, which are mediated by intercellular communications involving dendritic cells, bronchial epithelial cells and innate lymphoid cells [7, 8]. Whilst bronchial eosino
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Airway Remodelling in Asthma, of chronic inflammation [6]. However, close interactions tightly connect the cellular and molecular mechanisms underpinning airway inflammation and remodelling (Fig. 3.1), and both pathologic processes certainly contribute together to induce bronchial hyperresponsiveness as well as asthma persisten
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