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Titlebook: Arterial Mesenchyme and Arteriosclerosis; William D. Wagner,Thomas B. Clarkson Book 1974 The Editor(s) (if applicable) and The Author(s),

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Studies of Primate Arterial Smooth Muscle Cells in Relation to Atherosclerosisthis cell migration and proliferation, intracellular and extracellular lipids are deposited in association with formation of new extracellular connective tissue matrix constituents, including collagen, elastic fibers, and glycosaminoglycans.
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Production of Mucopolysaccharides, Collagen and Elastic Tissue by Aortic Medial Explantsuence the accumulation of lipids in the atheroma, thus aggravating the atherosclerotic process. On the other hand, the presence of collagen and elastic tissue may be beneficial in preventing extensive necrosis or in causing healing of necrotic lesions.
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Einführung in die Computeranimation Lee et al., 1970; McMillan and Stary, 1968; Poole et al., 1971) that the source of the mesenchymal or smooth muscle cells in the intima is medial cells that have proliferated and migrated into the intima.
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https://doi.org/10.1007/978-3-662-00199-8osaminoglycans (GAG), collagen,and elastin in the human intima to the amounts of intact intimai lipoprotein and of bound or precipitated lipid. It is clear that there are major gaps in our knowledge, and that this is an area in which further work is urgently required.
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