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Titlebook: Aquaporins; Baoxue Yang Book 20171st edition The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B

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期刊全称Aquaporins
影响因子2023Baoxue Yang
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发行地址Provides a state-of-the-art on recent developments and future directions in aquaporin research.Provides a systematic and comprehensive overview into aquaporins.Covers diverse aspects of aquaporin rese
学科分类Advances in Experimental Medicine and Biology
图书封面Titlebook: Aquaporins;  Baoxue Yang Book 20171st edition The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B
影响因子.This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 20 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order
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https://doi.org/10.1007/978-3-642-61769-0on, degradation, and protein interactions. Insight into the molecular mechanisms responsible for regulated aquaporin trafficking and synthesis is proving to be fundamental for development of novel therapeutic targets or reliable diagnostic and prognostic biomarkers.
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Die Lunge als myo-elastisches Systeml-shaped proteins surrounding internal pores that allow the passage of water and, in some family members, small solutes such as glycerol, play critical roles in regulating various skin parameters. The involvement of different aquaporin family members in skin function is discussed.
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