Titlebook: Applied Bioinformatics; An Introduction Paul M. Selzer,Richard J. Marhöfer,Andreas Rohwer Textbook 20081st edition Springer-Verlag Berlin H

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Sequence Comparisons and Sequence-Based Database Searches, sequences, construction of model structures for proteins, design and analysis of expression studies as well as a variety of other bioinformatic and biological experiments are all based on these analyses. Nature acts conservatively, i.e., it does not develop a new kind of biology for every life form

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The Decoding of Eukaryotic Genomes,the fi rst time one could analyze a complete genome, including both genes and their regulatory regions. Three years later, the sequencing of the fi rst multicellular eukaryotic genome, from the nematode ., was completed. Eukaryotic genomes are larger and far more complex than those from bacteria (se

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Systems Biology: The Functional Analysis of Genomes,cell, except sperm and eggs, has a complete set of genes. Obviously, however, a blood cell differs in its morphology and physiology from a liver cell. How, therefore, can these differences be explained if all cells have the same genetic material? The answer is simple. Not every gene is transcribed a

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Protein Structures and Structure-Based Rational Drug Design,ed upon water release) to form a polypeptide (see Chap. 2). Polypeptides can range in length from three to several hundred amino acids. The amino acid sequence of a given protein, also known as the primary structure, is genetically determined. It becomes fi xed during translation based on the information encoded in the mRNA.

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https://doi.org/10.1007/978-3-540-72800-9DNA; EST; Linux; algorithms; bioinformatics; biology; data base; databases; genome; genomics; nucleotide; prote